Radiance

Ideal for

  • Individuals with acne and discoloration
  • Those needing skin brightening
  • People with uneven texture
  • Individuals improving overall skin tone

Acne

Radiance

Azelaic Acid / Metformin / Progesterone / Spironolactone

Price range: $154.00 through $299.00

A comprehensive acne treatment that works to fade discoloration, reduce redness, and support an even skin tone while clearing the skin.

  • Targets multiple contributors to hormonal acne and hirsutism by combining anti‑inflammatory, antimicrobial, sebum‑regulating, and hormonal‑balancing ingredients.
  • Azelaic Acid: Reduces comedones and inflammation, fades hyperpigmentation, and smooths skin tone; effective within four weeks when used twice daily.
  • Metformin (topical): Helps modulate insulin resistance, which can reduce androgen‑driven oil production and acne.
  • Progesterone: Aids in hormonal balance, potentially improving sebum regulation and skin irritation (available in compounded topical form).
  • Spironolactone: Acts as an anti‑androgen to reduce sebum and acne, and can significantly improve hormonal acne and hirsutism; results typically appear over 1–3 months.
  • Azelaic Acid – A naturally occurring dicarboxylic acid that helps fight acne-causing bacteria, reduce skin inflammation, unclog pores, and fade post-acne marks, making Radiance effective for clearer and more even skin tone.
  • Metformin – Traditionally known as an insulin-regulating medication, when used in topical formulations like Radiance, it helps reduce androgen-driven oil production, balance hormonal activity in the skin, and improve acne associated with PCOS or insulin resistance.
  • Progesterone – A bioidentical hormone that supports sebum regulation and calms hormonally triggered irritation; in Radiance, it works to restore balance in the skin, making it less prone to flare-ups caused by hormonal fluctuations.
  • Spironolactone – A powerful anti-androgen that decreases the effects of excess male hormones on the skin; in Radiance, it reduces hormonal acne, oiliness, and unwanted facial hair growth, supporting a smoother and clearer complexion over time.
  • Cleanse your face thoroughly with a gentle cleanser and pat dry.
  • Apply a thin layer of Radiance cream directly to the affected areas (such as cheeks, jawline, or chin).
  • Use twice daily — once in the morning and once at night — unless directed otherwise by us.
  • Avoid contact with eyes, lips, and mucous membranes; if accidental contact occurs, rinse with water.
  • Apply sunscreen during the day while using Radiance, as some ingredients (like Azelaic Acid) may increase sun sensitivity.
  • Consistency is key — use it regularly for several weeks to see visible improvements.
  • Consult us before combining it with other prescription or hormonal treatments.

Q: What skin concerns is Radiance best suited for?
A: Radiance is best for hormonal acne, excess facial or body hair (hirsutism), and uneven skin tone often linked to PCOS. It combines Azelaic Acid, Metformin, Progesterone, and Spironolactone to target multiple root causes.

Q: How long does it take to see results with Radiance?
A: With consistent use, Radiance shows visible improvements in about 4 weeks due to Azelaic Acid, while Spironolactone and hormone-balancing effects from Metformin and Progesterone may take 1–3 months for full benefits.

Q: Are there any precautions or side effects when using Radiance?
A: Yes. Since Radiance contains hormone-active compounds, consult our healthcare provider before use, especially if pregnant or breastfeeding. Some users may experience mild irritation, dryness, or sensitivity.

Q: Can Radiance be used with other topical products?
A: Radiance can be combined with other skincare products, but avoid layering it with strong irritants such as harsh exfoliants or retinoids. It works well with moisturizers and sunscreens to minimize sensitivity.

Q: Is Radiance safe for all skin types?
A: Radiance is generally well-tolerated, especially since Azelaic Acid suits most skin types. However, people with very sensitive skin should patch test first and introduce the product gradually.

Q: Do I need to use sunscreen with Radiance?
A: Yes. Ingredients like Azelaic Acid can make skin more sensitive to sunlight. Daily use of sunscreen will help prevent irritation and protect your results.

  1. Banner Health. (2022, November 11). What is azelaic acid and its benefits? Banner Health.
  2. Mayo Clinic. (2025, January 31). Azelaic acid (topical route). Mayo Clinic.
  3. Trivedi, M. K., Shinkai, K., & Murase, J. E. (2017). A review of hormone‑based therapies to treat adult acne vulgaris in women. International Journal of Women’s Dermatology, 3(2), 83–90. Retrieved from PubMed Central.
  4. Ayatollahi, A., Samadi, A., Bahmanjahromi, A., & Robati, R. M. (2021). Efficacy and safety of topical spironolactone 5% cream in the treatment of mild to moderate acne vulgaris: A pilot study. Health Science Reports, 4(4), e352. Retrieved from PubMed Central.
  5. Sauer, N. (2024). The multiple uses of azelaic acid in dermatology. Journal Name, volume(issue), pages. Retrieved from PubMed Central.
  6. Verywell Health. (2024). Prescription topical acne treatments. Verywell Health.

A medical intake form is required prior to receiving a prescription. A licensed healthcare provider will review it and determine your eligibility for this product.

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Orange County, CA
(Virtual Services Nationwide)

(949) 990-4490

hello@eternellehealth.com

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