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brilliance

Ideal for

  • Individuals with uneven skin tone
  • Those with hyperpigmentation
  • People seeking brighter skin
  • Individuals improving skin clarity

Brightening

Brilliance

Azelaic Acid / Tranexamic Acid / Niacinamide

Price range: $154.00 through $299.00

Brilliance takes a focused approach to uneven pigmentation with azelaic acid and tranexamic acid, two ingredients studied for their effects on pathways involved in excess pigment formation. Niacinamide complements the formula with skin-barrier and moisture support. With no hydroquinone or retinoid in the formula, Brilliance offers our healthcare provider another option when developing an individualized plan for dark spots and uneven skin tone.

  1. Targets Uneven Pigmentation – Azelaic acid and tranexamic acid act on different processes associated with excess pigmentation.
  2. Addresses Dark Spots – Designed for areas of unwanted discoloration rather than changing your natural overall skin tone.
  3. Post-Inflammatory Tone Care – May be considered when uneven pigmentation develops following acne or other skin inflammation.
  4. Hydroquinone-Free Approach – Provides a pigmentation-focused option without hydroquinone for individuals whose treatment plan calls for a different approach.
  • Azelaic Acid has anti-inflammatory properties and influences processes involved in excess melanin production. It is used in dermatologic care for pigmentation concerns as well as acne and rosacea.
  • Tranexamic Acid has been studied topically for melasma and other forms of hyperpigmentation. It acts on signaling pathways involved in excess pigment production rather than bleaching the skin.
  • Niacinamide is a form of vitamin B3 that supports skin-barrier function and moisture retention and has also been studied for its role in improving the appearance of uneven pigmentation.
  • Smooth a thin layer of Brilliance over the areas of the face identified in your treatment plan once or twice daily, according to our healthcare provider’s instructions. Apply to clean skin and allow it to absorb before layering other skincare products. Frequency may be adjusted if dryness, stinging, or irritation develops.

Q: What is Brilliance designed to address?
A: Brilliance is intended for concerns involving uneven pigmentation, dark spots, and discoloration that can develop after skin inflammation. Our healthcare provider can determine the underlying type of pigmentation and whether this formula is appropriate.

Q: How is Brilliance different from Luminance?
A: Brilliance uses azelaic acid and tranexamic acid and does not contain hydroquinone or hydrocortisone. Luminance is a more intensive multi-ingredient formula containing hydroquinone and is generally used for a defined treatment period followed by reassessment or a break.

Q: Does Brilliance bleach the skin?
A: Brilliance is not intended to bleach or change your natural skin color. Its ingredients are used to address areas where excess pigmentation has created uneven tone or dark spots.

Q: Why combine azelaic acid and tranexamic acid?
A: The ingredients influence pigmentation through different biological pathways. Using them together allows the formula to approach excess pigmentation without relying on a single active ingredient.

Q: Can Brilliance be used for marks left after acne?
A: It may be considered for post-inflammatory hyperpigmentation, which can appear as darker areas after a blemish has healed. These marks are different from indented or raised acne scars.

Q: How long should I use Brilliance?
A: Your current protocol uses approximately 3–6 months to assess response. Pigmentation changes typically occur gradually, and our healthcare provider can determine whether continued treatment or an adjustment to your regimen is appropriate.

  1. ChemistConfessions. (2023). Azelaic, tranexamic, kojic acid… The chemists’ best hyperpigmentation ingredients guide. Chemist Confessions.
  2. Curology. (2023, July 26). Tranexamic acid vs. azelaic acid for melasma: What to know. Curology.
  3. Healthline. (2022, March 31). Tranexamic Acid for Skin: Benefits, Safety, How to Use. Healthline.
  4. Medical News Today. (2022, May 25). Tranexamic acid for skin care: Safety, benefits, and more. Medical News Today.
  5. WebMD. (2023). Azelaic Acid for Your Skin: What to Know. WebMD.
  6. SkinCeuticals. (2025). Azelaic Acid Benefits for Skin. SkinCeuticals.
  7. Sobhan, M., et al. (2023). A comparative study of 20% azelaic acid cream versus 5% tranexamic acid solution for the treatment of post inflammatory hyperpigmentation. Journal of Dermatological Treatment, 34(2), 1–7.
  8. Clinical peeling system study. (2025). In vitro and in vivo assessment of an innovative peeling system with azelaic and tranexamic acids for targeted hyperpigmentation reduction. Journal of Cosmetic Dermatology, 24(6), 543–552.
  9. Byrdie. (2025). Why Tranexamic Acid Is Skincare’s Trendiest Ingredient. Byrdie.
  10. Naturium. (2021). Tranexamic Acid vs Azelaic Acid – Which Is Right For You?. Naturium.
  11. Perfect Image. (2025). Tranexamic Acid vs Azelaic Acid: Key Differences, Benefits…. Perfect Image.

A medical intake form is required prior to receiving a prescription. A licensed healthcare provider will review it and determine your eligibility for this product. Click the Get Started button to fill up your intake form.​

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Orange County, CA
(Virtual Services Nationwide)

(949) 990-4490

hello@eternellehealth.com

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