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Spironolactone

Ideal for

  • Individuals experiencing hormonal breakouts
  • Those with recurring acne that has not responded to topical treatments
  • People with oily or combination skin
  • Individuals looking for a targeted approach to clearer skin

AcneOil Control

Spironolactone

Spironolactone

Price range: $134.40 through $230.00

Spironolactone Cream offers a topical approach for acne that may be influenced by androgen activity. Applied directly to affected skin, it may be considered for individuals with persistent or hormonally influenced breakouts when our healthcare provider determines this treatment is appropriate.

  • Targets Hormonal Acne Concerns – Takes an anti-androgenic approach to breakouts that may be influenced by hormonal activity.
  • Localized Application – Applied directly to acne-prone areas rather than taken orally.
  • Fits Into Personalized Acne Care – Can be considered as part of an individualized treatment plan based on the type and pattern of your breakouts.
  • Spironolactone has anti-androgenic activity, meaning it can interfere with the effects of androgen hormones. While oral spironolactone is commonly used in the medical management of hormonal acne, topical one is used differently and requires individualized medical evaluation.
  • Apply a thin layer of Spironolactone Cream directly to acne-prone or affected areas once or twice daily, according to your prescribed regimen. Allow the cream to absorb before applying other skincare products. Our healthcare provider may adjust frequency based on your skin’s response and tolerance.

Q: What type of acne is Spironolactone Cream intended for?
A: It may be considered when breakouts appear to have a hormonal or androgen-related component. Our healthcare provider will evaluate your acne pattern and health information before recommending treatment.

Q: How is topical different from oral spironolactone?
A: One is applied directly to the skin and the other is taken systemically by mouth. They should not be considered interchangeable, and their dosing, absorption, evidence, and potential risks differ.

Q: Where should I apply the cream?
A: Apply a thin layer to the areas identified in your treatment plan rather than using more product than prescribed. Frequency is generally once or twice daily based on our healthcare provider’s instructions.

Q: When should my treatment be reassessed?
A: Acne treatment typically requires time to evaluate. Our healthcare provider may review your progress after approximately 8–12 weeks and decide whether continued or adjusted treatment is appropriate.

Q: Can Spironolactone Cream cause side effects?
A: Topical treatment may cause local reactions such as dryness, redness, or irritation. Because spironolactone has anti-androgenic activity, our healthcare provider will also review relevant medical considerations before prescribing it.

  1. Spironolactone tablets. (2026, February 27). Retrieved from Cleveland Clinic.
  2. Ayatollahi, A., Samadi, A., Bahmanjahromi, A., & Robati, R. M. (2021). Efficacy and safety of topical spironolactone 5% cream in the treatment of acne: A pilot study. Health Science Reports, 4(3), e317. Retrieved from Pub Med.

A medical intake form is required prior to receiving a prescription. A licensed healthcare provider will review it and determine your eligibility for this product. Click the Get Started button to fill up your intake form.​

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Eternelle - Health and Wellness

Orange County, CA
(Virtual Services Nationwide)

(949) 990-4490

hello@eternellehealth.com

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