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Luminance

Ideal for

  • Individuals with dark spots
  • Those with melasma
  • People with uneven skin tone
  • Individuals seeking brighter complexion

Brightening

Luminance

Azelaic Acid / Hydrocortisone / Hydroquinone / Kojic Acid with Green Tea EGCG / Resveratrol

Price range: $154.00 through $299.00

Luminance is a targeted treatment for melasma and areas of persistent hyperpigmentation. The formula combines hydroquinone and kojic acid with azelaic acid to address excess pigmentation through complementary pathways, while hydrocortisone helps manage inflammation. Green tea EGCG and resveratrol add antioxidant components to this multi-ingredient approach. Our healthcare provider will determine whether Luminance is appropriate for your pigmentation concerns and how long treatment should continue.

  • Targets Excess Pigmentation – Hydroquinone and kojic acid act on pathways involved in melanin production to address areas of unwanted pigmentation.
  • Melasma-Focused Care – Brings several pigmentation-focused ingredients together for individuals whose treatment plan addresses melasma or persistent uneven pigmentation.
  • Addresses Pigment + Inflammation – Azelaic acid and hydrocortisone add anti-inflammatory activity alongside the formula’s pigment-focused ingredients.
  • Antioxidant Components – Green tea EGCG and resveratrol provide complementary antioxidant activity as part of the overall formulation.
  • Azelaic Acid has anti-inflammatory activity and can influence processes involved in excess pigmentation, making it useful when uneven tone occurs alongside skin inflammation.
  • Hydrocortisone is a corticosteroid that reduces inflammatory activity in the skin. Because prolonged topical corticosteroid use can cause adverse effects, treatment duration should follow our healthcare provider’s instructions.
  • Hydroquinone reduces melanin production by inhibiting tyrosinase, an enzyme involved in pigment formation. It is commonly used under medical supervision for hyperpigmentation concerns.
  • Kojic Acid also acts on tyrosinase and is used topically to help address the appearance of excess pigmentation.
  • Green Tea EGCG is a plant-derived antioxidant studied for its antioxidant and skin-conditioning properties.
  • Resveratrol is a polyphenol with antioxidant properties included to provide complementary antioxidant support within the formula.
  • At night, apply a thin layer of Luminance only to the hyperpigmented areas identified in your treatment plan. Avoid the eyes, lips, broken skin, and unaffected areas unless instructed otherwise. Treatment is generally used for a defined period, such as 8–12 weeks, followed by a break or reassessment by our healthcare provider. Do not continue hydroquinone- or hydrocortisone-containing treatment beyond the prescribed period without medical guidance.

Q: What is Luminance designed to address?
A: Luminance is intended for targeted treatment of hyperpigmentation concerns such as melasma and persistent dark patches when our healthcare provider determines this combination is appropriate.

Q: How does hydroquinone work on dark spots?
A: Hydroquinone inhibits tyrosinase, an enzyme involved in producing melanin. Reducing melanin production can gradually improve the appearance of areas with excess pigmentation.

Q: Why does Luminance contain more than one pigmentation ingredient?
A: Hyperpigmentation involves several biological processes. Hydroquinone, kojic acid, and azelaic acid have different properties relevant to pigmentation, allowing the formula to approach uneven tone through more than one pathway.

Q: Why is hydrocortisone included?
A: Hydrocortisone reduces inflammation in the skin. It is not included simply as a cosmetic brightening ingredient and should only be used for the duration prescribed because prolonged corticosteroid exposure can cause unwanted skin effects.

Q: Should I apply Luminance all over my face?
A: Not unless specifically instructed. Luminance is intended to be applied in a thin layer to the areas identified by our healthcare provider as requiring treatment.

Q: Why does the treatment include a break?
A: Hydroquinone and topical corticosteroids require appropriate duration and monitoring. After an initial treatment period of approximately 8–12 weeks, our healthcare provider can evaluate your response and determine whether a break, maintenance approach, or different treatment is appropriate.

  1. Bloom MD. (n.d.). Luminance (Azelaic Acid / EGCG / Hydrocortisone …). Bloom MD.
  2. Skin Clique. (n.d.). Brightening Prescription Treatments: Luminance Cream. Skin Clique.
  3. Allure. (n.d.). Dermatologists recommend personalized blends including azelaic acid, kojic acid, hydrocortisone, and hydroquinone. Allure.
  4. Health.com. (2025). Kojic acid, derived from fermentation, reduces melanin for brighter skin; high concentrations may cause irritation. Health.
  5. Verywell Health. (2022). Hydroquinone treats discolorations like melasma and age spots, though long-term use carries some risk. Verywell Health.
  6. Vogue. (2025). Azelaic acid is a gentle, effective tyrosinase inhibitor ideal for sensitive skin; supports melasma reduction. Vogue.
  7. Zhao, Y., & Ding, C. (2018). Effects of hydrocortisone on regulating inflammation, hemodynamic stability, and preventing shock in severe sepsis patients. Medical Science Monitor, 24, 3612–3619. National Library of Medicine.
  8. Sun, J., Yang, R., Fang, L., Li, Y., Xing, W., Sun, M., Wu, L., Wu, Q., & Gong, T. (2026). Effects of resveratrol supplementation on multiple health outcomes: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials. Nutrition Journal, 25(1). Springer Nature.

A medical intake form is required prior to receiving a prescription. A licensed healthcare provider will review it and determine your eligibility for this product. Click the Get Started button to fill up your intake form.​

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Orange County, CA
(Virtual Services Nationwide)

(949) 990-4490

hello@eternellehealth.com

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