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Unblemished

Ideal for

  • Individuals with hormonal acne
  • Those with persistent breakouts
  • People with oily skin
  • Individuals needing acne control

Acne

Unblemished

Azelaic Acid / Clindamycin / Spironolactone

Price range: $154.00 through $299.00

Unblemished is designed for breakouts that may involve more than one contributing factor. It combines azelaic acid, clindamycin, and spironolactone to address inflammatory acne, acne-associated bacteria, and androgen-related activity within one topical treatment. Our healthcare provider can determine whether this combination fits your acne pattern and individual treatment needs.

  • Three-Pronged Acne Care – Brings together ingredients that address different factors associated with acne rather than relying on a single active ingredient.
  • Inflammatory Blemish Care – Azelaic acid and clindamycin have properties relevant to inflammatory acne.
  • Hormonal Acne Approach – Spironolactone provides anti-androgenic activity for breakouts that may have a hormonal component.
  • Post-Blemish Tone Support – Azelaic acid may also help address the appearance of uneven pigmentation that can remain after blemishes.
  • Azelaic Acid has anti-inflammatory and antimicrobial activity and is used topically in acne care. It can also be useful when uneven pigmentation accompanies blemishes.
  • Clindamycin is a topical antibiotic that reduces susceptible bacteria associated with acne and is used to help manage inflammatory lesions.
  • Spironolactone has anti-androgenic activity. In a topical acne formula, it may be considered when androgen activity is thought to contribute to recurring or hormonally influenced breakouts.

Apply a thin layer of Unblemished to acne-affected areas once or twice daily according to your prescribed regimen. Use on clean skin and avoid the eyes, lips, and irritated areas. Because Unblemished contains the antibiotic clindamycin, treatment length and continued use should follow the plan established by our healthcare provider rather than being used indefinitely without reassessment.

Q: What makes Unblemished different from a basic acne cream?
A: Instead of focusing on one aspect of acne, Unblemished combines three ingredients with different roles: azelaic acid, an antibiotic, and an anti-androgenic medication.

Q: Is Unblemished specifically for hormonal acne?
A: Not exclusively. Spironolactone may be relevant when androgen activity contributes to breakouts, while azelaic acid and clindamycin address other aspects of acne. Our healthcare provider will evaluate whether your acne pattern is appropriate for this combination.

Q: Can it help with marks left behind by breakouts?
A: Azelaic acid is used in skincare for uneven pigmentation and may be helpful when discoloration accompanies acne. It should not be expected to remove acne scars or guarantee that post-blemish marks will disappear.

Q: Why does Unblemished contain an antibiotic?
A: Clindamycin helps reduce susceptible bacteria associated with inflammatory acne. Antibiotic-containing acne treatments require appropriate medical oversight to help limit unnecessary or prolonged antibiotic exposure.

Q: How long should I give the treatment before evaluating it?
A: Acne typically changes gradually. An initial period of approximately 8–12 weeks may be used to evaluate your response before our healthcare provider decides whether treatment should continue, change, or stop.

Q: Can Unblemished irritate my skin?
A: Redness, dryness, burning, itching, or irritation can occur with topical acne treatments. Contact our healthcare provider if reactions are persistent, significant, or concerning.

  1. Feng, X. (2024). Azelaic Acid: Mechanisms of Action and Clinical Applications. PMC.
  2. Sauer, N. (2024). The multiple uses of azelaic acid in dermatology. PMC.
  3. NursingCenter. (n.d.). Azelaic Acid in Acne Vulgaris. NursingCenter.
  4. Verywell Health. (n.d.). Prescription Topical Acne Treatments. Verywell Health.
  5. Rehan, S. T. (2023). Role of topical spironolactone in the treatment of acne. PubMed.
  6. Ayatollahi, A. (2021). Efficacy and safety of topical spironolactone 5% cream in acne. PubMed.
  7. Noaimi, A. (2021). Treatment of Acne Vulgaris by Topical Spironolactone vs. Clindamycin Solution. PubMed.

A medical intake form is required prior to receiving a prescription. A licensed healthcare provider will review it and determine your eligibility for this product. Click the Get Started button to fill up your intake form.​

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Orange County, CA
(Virtual Services Nationwide)

(949) 990-4490

hello@eternellehealth.com

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